Bridging the knowledge gap
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Date
2025
Authors
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Journal ISSN
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Publisher
Krupanidhi College of Pharmacy
Abstract
Pharmacovigilance plays a crucial role in assessing the risk-benefit ratio of medications, promoting their
safe, rational, and effective use, and ultimately improving patient safety and care. Nurses play a fundamental
role in drug administration and monitoring the therapeutic and non-therapeutic effects of drugs. The
study aimed to assess knowledge, attitudes, and practices regarding pharmacovigilance among newly
graduated registered nurses in Lesotho, both before and after an educational intervention. This study
utilized a questionnaire-based educational intervention with a pre- and post-test design, involving newly
graduated registered nurses. A link to a 15-item pre-validated electronic questionnaire assessing knowledge,
attitudes, and practices related to pharmacovigilance was distributed to newly graduated registered nurses
before and after an educational intervention. Ethical clearance and consent from the respondents were
secured prior to the start of the study. A total of 197 newly graduated registered nurses from 6 nurse
training institutions participated in this pre- and post-KAP questionnaire study. When comparing the
KAP of pharmacovigilance before and after the educational intervention, the increase in correct response
rates was statistically significant (P < 0.001). The training evaluation received positive feedback from
the participants. Incorporating a pharmacovigilance module into pre-service nurse training is essential.
Additionally, continuing in-service and hands-on nurse training on adverse drug reaction reporting can
enhance the KAP of pharmacovigilance and improve adverse drug reaction reporting in nursing practice.
The concepts of pharmacovigilance and adverse drug reaction reporting should be further reinforced, as
there is significant potential for growth in this area