Abstract:
Background: Low- and middle-income countries including Lesotho are
faced with a huge burden of end-stage kidney disease in people
experiencing human immune virus (HIV), hypertension (HTN) and diabetes
mellitus (DM).
Objectives: To assess the comorbidity, mortality rate and evaluate the
haemodialysis adequacy in patients with end-stage kidney disease in
Motebang government hospital.
Methods: A retrospective study was conducted in 142 adult male and female
patients enrolled for haemodialysis from 1st October 2017 to 30th June 2023
in Motebang government hospital. Patient’s characteristics and clinical
outcomes data were analysed using descriptive statistics
Results: Among 142 patients enrolled, there were 84 (59.2%) males and 58
(40.8%) females. 19 (13.4%) patients were below 34 years while 33 (23.3%)
patients were between 45 and 64 years. In all age groups, 41 (28.9%) patients
had HIV, 37 (26.1%) patients had HTN alone and 24 (16.9%) patients had
combination of HTN and DM. In 63 deceased patients, there were 36 (57.1%)
males and 27 (42.7%) females. Among deceased, 18 (28.5%) patients had HIV,
15 (23.8%) had combination of HTN and DM, 14 (22.3%) patients had HTN
alone, while all the patients (99.3%) were also anaemic. Since 2017, 19 (30.2%)
patients died in 2020, 12 (19%) died in 2022 while only 4 (6.3%) patients died
up to date (June 2023). Among 79 patients, only 1 (1.3%) patient had urea-
reduction ratio (URR) greater than 65%.
Conclusions: Chronic diseases are the major risks factors in patients with
end-stage kidney disease in Motebang hospital. Haemodialysis adequacyshould form the integral part of monitoring in patients with end-stage kidney
disease to prolong life
